Wednesday, July 30, 2008

Penicillium mold allergy does NOT mean a penicillin allergy

I have been asked many times if a positive allergy skin test to the mold Penicillium means that the patient is also allergic to Penicillin, the antibiotic. The answer is no.

The mold Penicillium chrysogenum (also known as Penicillium notatum) secretes the antibiotic Penicillin into the space outside its cells. The goal is to kill ordinary bacteria around the mold, because they compete with the mold for food and water. This can be seen as a clear space when Penicillium is grown in a culture dish. This was first noticed by Alexander Fleming in 1928. To read about the story in detail, go to http://botit.botany.wisc.edu/toms_fungi/nov2003.html. The antibiotic was named because it came from the mold Penicillium. Structurally they are completely different.

If you have questions about Pencillin or Penicillium allergies, ask your doctor.

1 comment:

B said...

However, on the flip side, If you are Negative for an allergy to Penicillium, does his mean you will also not be allergic to Pennicillin? if no, what is the test for allergy to penicillin?

This website is certified by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
 
My Zimbio Medicine Blogs - BlogCatalog Blog Directory